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Squalene – Sebum-Mimicking Barrier Repair for Skincare

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A sebum-like emollient close to human skin lipids that supports barrier repair and antioxidant defense, a popular pick for serum oils, creams and baby care.

  • Mimics human sebum for a natural, skin-like feel
  • Supports barrier repair while helping defend against oxidation
  • A popular emollient in serum oils, creams and baby skincare

    99% Squalene Oil (CAS 111-02-4) | Plant-Derived Cosmetic Raw Material

    99% Squalene Oil (CAS 111‑02‑4)

    High-Purity Plant-Derived Squalene For Skin Barrier Repair Serum, Facial Oil, Cream & Hair Care, Natural Antioxidant Emollient, Low Irritation
    ✅ PREMIUM NATURAL COSMETIC INGREDIENTS ✅ BUILDING BLOCKS FOR EXCEPTIONAL BEAUTY PRODUCTS
    Squalene-Oil Plant-Derived Cosmetic Raw Material

    Product Specification

    Item Specification

    Product Name

    Squalene

    CAS No.

    111‑02‑4

    INCI Name

    SQUALENE

    Purity

    ≥99.0%

    Appearance

    Colorless to pale yellow clear oily liquid

    Solubility

    Insoluble in water; freely soluble in oils & organic solvents

    Recommended Dosage

    1%‑10% in cosmetic formulation

    MOQ

    1kg

    Shelf Life

    18 months under proper sealed storage

    Source

    Plant‑derived (Olive / Sugarcane fermentation, non‑shark source)

    What Is Squalene?

    Squalene (CAS 111‑02‑4) is a natural unsaturated triterpene lipid, an important constituent of human skin sebum, widely applied as emollient, barrier repair and antioxidant raw material for premium skincare formulas. It mimics skin’s native lipid composition, enhances skin softness, reduces transepidermal water loss, and neutralizes free radicals triggered by UV and environmental stressors. Compared with squalane, squalene brings stronger antioxidant capacity for anti‑aging and photoprotection, yet requires careful anti‑oxidation protection during formulation and storage.

    As a reliable China bulk manufacturer and wholesale supplier, Aogubio supplies 99% plant‑sourced squalene oil for cosmetic manufacturers worldwide. We support facial oil, repairing cream, serum, hair care and makeup formulation, offering free samples, full COA/MSDS/TDS documents and global door‑to‑door shipping.

    Core Advantages Of Our 99% Squalene

    Plant‑derived & Sustainable

    Non‑shark, renewable plant‑fermented source, compliant with global cruelty‑free cosmetic trends, safe and eco-friendly for high-end cosmetic formulas.

    High Purity 99%

    Strict quality control, low peroxide value, batch‑to‑batch stable quality, perfectly suitable for large‑scale cosmetic industrial production.

    Excellent Skin Compatibility

    Identical to human sebum component, fast skin penetration, non‑greasy texture, friendly for sensitive skin and lipid‑deficient damaged skin.

    Natural Antioxidant Property

    Effectively scavenges singlet oxygen and free radicals, relieves oxidative skin damage caused by UV exposure and environmental pollution, delivers anti-aging effects.

    Multi-scene Formulation Compatibility

    Easy to incorporate into all oil‑phase systems, adaptable for leave‑on skincare, hair care and color cosmetic formulas.

    Full Document & Flexible Supply

    Each batch supports complete COA, MSDS, TDS documents. Provide free sample test, small-batch trial and large-volume bulk orders.

    How Squalene Works On Skin Barrier & Antioxidation

    Squalene naturally exists within human sebum lipid layer. Topical replenishment reinforces skin barrier function, lowers TEWL (transepidermal water loss), alleviates dryness, tightness and flaking skin. Chemically it quenches reactive singlet oxygen and free radicals to mitigate photo‑oxidative damage, assisting anti‑aging and dullness improvement.

    Important note: Squalene contains unsaturated double‑bonds; it is sensitive to light, heat and oxygen. Nitrogen‑blanketing, anti‑oxidant assistants and opaque packaging are recommended for finished products to avoid oxidation deterioration. It performs better in night‑oriented repairing formulas.

    Main Functions & Cosmetic Application Fields

    Skin Benefits of Squalene

    • • Reinforce skin lipid barrier, reduce skin water loss
    • • Natural antioxidant, resist UV‑induced oxidative stress
    • • Soothe dry, tight and irritated sensitive skin
    • • Improve skin softness, smoothness and suppleness
    • • Nourish hair, reduce frizz, repair damaged hair cuticles

    Formulas Suitable For Squalene Raw Material

    • • Repairing facial oil & antioxidant serum
    • • Moisturizing & anti‑aging facial cream / lotion
    • • Soothing after‑sun care products
    • • Hair oil, hair mask and leave‑on hair conditioner
    • • Lip care products, foundation, primer and other color cosmetics
    • • Body nourishing skincare oil

    Formulation Guide: Dosage, Solubility & Matching Tips

    Recommended dosage: 1%‑10% of total formula weight. For sensitive‑skin products, keep within 1‑5%.

    Solubility: Oil‑soluble raw material, add to oil‑phase components. Process temperature should not exceed 60℃. Avoid prolonged high‑temperature heating.

    Recommended matching ingredients: Synergistic effect when combined with squalane, ceramides, vitamin E, bisabolol, hyaluronic acid; Vitamin E is strongly suggested as anti‑oxidant stabilizer to restrain squalene oxidation.

    Notes for formulation:

    • Avoid long‑term exposure to air, high temperature, strong light.
    • Use amber / opaque packaging for finished cosmetics.
    • Nitrogen filling during production is highly advised.
    • Not suitable for extreme high‑temperature sterilization process.
    GMP ISO22716 Alpha Arbutin Manufacturing WorkshopGMP ISO22716 Alpha Arbutin Manufacturing WorkshopGMP ISO22716 Alpha Arbutin Manufacturing Workshop

    Squalene VS Squalane Full Comparison

    Item

    Squalene

    Squalane

    Purity

    99%

    99%

    Antioxidant Activity

    High (unsaturated double bonds)

    Low (saturated structure)

    Typical Usage Dosage

    1‑10%

    1‑20%

    Oxidation Stability

    Poor (sensitive to light & air)

    Excellent

    Skin‑barrier Repair

    Good

    Excellent

    Suitable Scenarios

    Night‑time antioxidant repairing formulas

    Day & night all‑round skincare

    Cost Level

    Medium‑high

    Medium

    Packaging, MOQ & Global Shipping Details

    Packaging, MOQ & Global Shipping Details (1)
    Packaging, MOQ & Global Shipping Details (1)
    Packaging, MOQ & Global Shipping Details (2)
    Packaging, MOQ & Global Shipping Details (2)
    • Sample package: 10g, 50g, 100g free testing samples (amber sealed bottle, nitrogen‑filled)
    • Small bulk: 1kg / 5kg amber drum / aluminium foil sealed drum
    • Large bulk: 25kg food‑grade fiber drum with inner anti‑oxidation sealing
    • MOQ: 1kg
    • Shipping: Global door‑to‑door shipping available. We support DHL, FedEx, sea freight and air freight.
    • Lead time: 3‑7 working days for sample; 7‑15 working days for bulk order.
    • Custom packing: Service is available upon request for large orders.

    Storage & Shelf Life Standard

    Storage Conditions

    Keep tightly sealed, nitrogen‑filled if possible; store in cool, dry and dark place. Avoid high temperature, direct sunlight and long‑time air contact. Keep away from strong oxidants.

    Standard Shelf Life

    Under correct sealed storage conditions, shelf life is 18 months. Once opened, use up quickly.

    Certifications & Compliance Documents (COA, MSDS, TDS)

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    Our 99% Plant‑derived Squalene complies with mainstream cosmetic raw‑material requirements:

    • Listed in EU CosIng database
    • Compliant for global cosmetic raw‑material registration
    • ISO22716 & GMP production management system
    • Each batch provides full COA, MSDS and TDS documents
    • Support third‑party independent testing for customers’ lab verification

    We serve cosmetic manufacturers from Europe, Southeast Asia, Middle East and other regions, providing stable bulk raw‑material supply for finished skincare, haircare and makeup brands.

    Frequently Asked Questions

    • Q1: Why must squalene avoid light and air during storage & production?

      A: Squalene has multiple unsaturated double‑bonds. Light, heat and oxygen will trigger oxidation, raise peroxide value and cause oil deterioration. Nitrogen filling, opaque containers and adding vitamin‑E antioxidant are recommended.
    • Q2: Can squalene mix with squalane in cosmetic formula?

    • Q3: What is your MOQ for bulk squalene wholesale?

    • Q4: Do you provide custom packaging service for bulk orders?

    • Q5: Is squalene safe for sensitive‑skin cosmetic products?

    • Q6: How can I get full COA and MSDS document?

    • Q7: What is your bulk‑order lead time for squalene oil?

    Get Wholesale Quote & Free Testing Sample

    If you are looking for reliable bulk supplier of 99% Alpha Arbutin Powder, please feel free to contact us.
    We offer free lab test sample, complete technical documents and professional formulation suggestion support for your cosmetic R&D team.
    Send Inquiry For Sample & Bulk Price

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    Global Business Contact:

    WhatsApp: 008618066950297

    Official Website: www.aogebio.com

    Factory Address: Xi'an, Shaanxi, China (GMP cosmetic raw material production base)