Madecassoside – Centella Soothing Repair Active
Madecassoside is the main soothing active in centella extract. It calms reactive skin, supports the barrier and helps collagen synthesis, which is why repair creams and masks use it.
- Soothing active aimed at reactive, easily flushed skin types
- Supports the skin barrier and helps collagen synthesis
- Fits repair creams, masks and after-sun product lines
Madecassoside Cosmetic Grade | Refined Centella Asiatica Isolated Active Bulk‑Aogebio
Madecassoside
Madecassoside Cosmetic Grade High‑Purity Madecassoside, Potent Anti‑Inflammatory & Barrier‑Repairing Active For Repair Serum, Calming Cream, Sensitive Skin Care & Post‑Procedure Skincare Formulas
Product Specification
| Item | Specification |
|---|---|
| Product Name | Madecassoside |
| INCI Name | Madecassoside |
| CAS No | 34540‑22‑2 |
| Appearance | Fine white to off‑white crystalline powder |
| Source | Purified isolation & refinement from Centella Asiatica (Gotu Kola) whole herb |
| Purity | ≥90% (HPLC, custom 80% / 85% /95% optional) |
| Solubility | Soluble in water, polyols and ethanol; insoluble in non‑polar oils |
| Recommended Dosage | 0.1%‑1.0% in cosmetic formulation |
| MOQ | 1kg |
| Shelf Life | 24 months under sealed cool‑dark dry storage |
| Grade | Cosmetic High‑Purity Grade |
What Is Madecassoside?
Madecassoside is a high‑purity isolated triterpenoid saponin purified from Centella Asiatica (Gotu Kola), a well‑known herbal skin‑repair botanical. Unlike crude Centella Asiatica extract with mixed variable components, Madecassoside is a single standardized active molecule with stable batch‑to‑batch potency. It effectively inhibits inflammatory response, boosts type I & III collagen synthesis, enhances ceramide & filaggrin production to reinforce skin barrier, delivers antioxidant protection against free radicals and UV‑triggered skin damage.
It works excellently for sensitive, irritated, damaged and post‑treatment skin. Widely adopted in calming serums, barrier repair creams, post‑laser recovery gels, acne‑repair skincare and soothing mask products. Aogebio supplies bulk high‑purity Madecassoside powder, providing free samples, full qualification documents and global one‑stop shipping services for cosmetic manufacturers.
Core Advantages Of Our Madecassoside
High‑Purity Isolated & Consistent Potency
Adopts multi‑step extraction, macroporous resin purification and recrystallization process. Low impurity content, odorless white powder, HPLC‑verified purity. Provides predictable efficacy compared with variable crude centella extracts, ideal for high‑end clean‑beauty cosmetic formulas.
Powerful Targeted Soothing & Barrier Repair
Directly modulates NF‑κB inflammatory pathway to reduce irritated redness and skin sensitivity; stimulates fibroblast activity and collagen generation, accelerates skin tissue repair, relieves post‑damage skin discomfort, helps fade post‑acne marks and rough skin texture.
Good Water‑Solubility & Wide Formula Compatibility
Water‑soluble active ingredient, dissolves clearly in water‑phase and polyol systems. Compatible with most cosmetic raw materials: plant extracts, panthenol, hyaluronic acid, allantoin, bisabolol and various humectants. Fits aqueous toners, serums, lotions, creams, gels and mask systemsmadecassos....
Mild & Low‑Irritation, Non‑Comedogenic
Purified botanical‑derived single molecule, free of irritating impurities. Non‑comedogenic, safe for sensitive skin, acne‑prone skin, fragile post‑procedure skin and gentle skincare for delicate skin.
Stable Quality & Flexible Supply
Strict HPLC batch testing, stable lot‑to‑lot quality, suitable for large‑scale industrial production. Support sample testing, small‑batch trial order and large‑bulk customization with adjustable purity options.
How Madecassoside Works On Skin
Madecassoside dissolves in aqueous phase and penetrates into skin surface layer. It suppresses release of pro‑inflammatory cytokines to ease redness, stinging and skin irritation triggered by external stimulus, UV‑exposure or cosmetic‑related irritation. It promotes fibroblast proliferation, accelerates type I & III collagen synthesis, supports ceramide and filaggrin expression to rebuild impaired skin barrier function. It also neutralizes skin‑damaging free radicals to reduce oxidative stress, improves rough skin texture, relieves post‑acne inflammation marks and helps skin return to stable, smooth and healthy status.
Main Functions & Cosmetic Application Fields
Core Efficacy Benefits
- • Powerful anti‑inflammatory & soothing, relieve skin redness, stinging and sensitivity
- • Repair impaired skin barrier, strengthen skin self‑defense capability
- • Boost collagen synthesis, improve skin elasticity, anti‑aging & anti‑fine‑line
- • Relieve post‑inflammatory marks, assist post‑acne and post‑procedure skin recovery
- • Antioxidant effect against UV‑ and pollution‑caused free‑radical damage
- • Improve rough skin texture, stabilize fragile sensitive skin condition
Suitable Cosmetic Formulas
- • Sensitive‑calming repair serums & soothing toners
- • Barrier‑repair facial cream & lotion for irritated skin
- • Post‑laser / post‑treatment repair gel & mask
- • Acne‑after‑care repairing skincare products
- • Soothing facial mask, ampoule essence
- • Clean‑beauty gentle skincare and dermatological‑friendly cosmetics
Formulation Guide: Dosage, Solubility & Matching Tips
Recommended dosage: 0.1%‑1.0% of total formula weight; 0.1%‑0.3% for daily maintenance skincare; 0.5%‑1.0% for intensive repair formulas for damaged skin.
Solubility: Water‑soluble triterpenoid saponin; dissolve in water‑phase or polyol phase. Suggest adding at cooling phase below 45‑60℃ to retain maximum bioactivity; avoid long‑time high‑temperature heating above 80℃.
Recommended matching ingredients: Perfectly matched with Panthenol, Sodium Hyaluronate, Allantoin, Bisabolol, Centella Asiatica Extract, Squalane to amplify soothing and barrier‑repair performance.
Formulation Notes:
- -Keep formula pH between 5.0‑7.0; avoid strong acid / strong‑alkali environment to prevent molecular hydrolysis and activity loss.
- -Do not sustain high temperature above 80℃ for long time to prevent active degradation.
- -Dissolve fully before mixing with other phases, ensure uniform distribution in finished products.
- -Seal and store in cool‑dark dry environment to avoid moisture and direct sunlight.
Packaging, MOQ & Global Shipping Details
- Sample package: 10g, 50g, 100g free testing samples (sealed aluminum foil bag)
- Small bulk: 1kg / 5kg sealed moisture‑proof aluminium foil bag
- Large bulk: 25kg moisture‑proof fiber drum with inner sealed bag
- MOQ: 1kg
- Shipping: Global door‑to‑door shipping, support DHL, FedEx, air and sea freight
- Lead time: 3‑7 working days for samples; 7‑15 working days for bulk orders
- Custom service: Custom purity specification, custom packaging and private label for large orders
Storage & Shelf Life Standard
Storage Conditions
Store in cool, dry, dark and low‑temperature environment, keep tightly sealed and moisture‑proof. Avoid high‑temperature exposure, direct sunlight and humid atmosphere to prevent moisture absorption, discoloration and activity attenuation.
Standard Shelf Life
24 months under standard sealed cool‑dark dry storage conditions.
Certifications & Compliance Documents (COA, MSDS, TDS)
Our Madecassoside meets global cosmetic raw‑material safety standards:
- EU CosIng database registered ingredient
- ISO22716 & GMP cosmetic production system certification
- Each batch equipped with complete COA, MSDS, TDS documents, HPLC test report
- Support third‑party professional testing and verification
We provide stable and high‑quality plant‑derived cosmetic active raw materials for global daily chemical and cosmetic manufacturers.
Frequently Asked Questions
-
Q1: What is the difference between Madecassoside and Centella Asiatica Extract?
-
Q2: Is Madecassoside suitable for sensitive‑skin skincare formulas?
-
Q3: Will Madecassoside clog pores?
-
Q4: What is your minimum order quantity and sample policy?
A: MOQ is 1kg. Free test samples are provided for customer formula research and trial production.
Get Wholesale Quote & Testing Sample
Leave Your Message
Global Business Contact:
WhatsApp: 0086‑18091843361
Official Website: www.aogebio.com
Factory Address: Xi'an, Shaanxi, China