Dipotassium Glycyrrhizate
98% Dipotassium Glycyrrhizate Powder CAS 68797-35-3 | Bulk Cosmetic Raw Material Manufacturer
Dipotassium Glycyrrhizate
High purity 98% Dipotassium Glycyrrhizate powder CAS 68797-35-3, water-soluble licorice-derived cosmetic raw material for skin soothing, anti-redness and anti-irritation. Compliant with IECIC, CosIng & CIR safety assessment. GMP factory, free sample, bulk wholesale, global door-to-door shipping.Product Specification
| Item | Specification |
|---|---|
Product Name |
Dipotassium Glycyrrhizate |
INCI Name |
Dipotassium Glycyrrhizate |
CAS No. |
68797-35-3 |
EC Number |
272-296-1 |
Purity |
≥98.0% (HPLC) |
Appearance |
White to off-white fine crystalline powder |
Solubility |
Highly soluble in water; soluble in glycerin, propylene glycol; insoluble in oil |
pH (1% Aqueous Solution) |
5.0-6.0 |
Recommended Dosage |
Leave-on:0.1%-1.0%; Rinse-off:0.1%-0.5% |
MOQ |
1kg |
Shelf Life |
2 years under proper sealed storage |
What Is Dipotassium Glycyrrhizate?
Dipotassium Glycyrrhizate (CAS 68797-35-3) is a purified triterpenoid salt derived from licorice root Glycyrrhiza glabra / Glycyrrhiza uralensis, widely accepted cosmetic soothing active, evaluated and approved by CIR, EU CosIng and China IECIC inventory.
It exerts anti-inflammatory, anti-redness and skin-calming effects by inhibiting inflammatory enzymes and histamine release. It relieves stinging, itching and redness caused by UV exposure, chemical actives and external irritation, helps repair irritated skin barrier. Different from crude licorice extract, this standardized single-ingredient powder features stable batch quality, high water-solubility and good skin compatibility.
As a reliable Chinese bulk manufacturer & wholesale supplier, we supply 98% Dipotassium Glycyrrhizate powder for cosmetic factories worldwide. It is widely formulated into serum, cream, mask, toner, after-sun care and scalp care products. We provide free test samples, complete COA, MSDS, TDS documents and global door-to-door shipping service.
Core Advantages Of Our 98% Dipotassium Glycyrrhizate
Standardized High-Purity Raw Material ≥98% HPLC
Strict HPLC quality control, low impurity content, consistent batch performance for large-scale cosmetic manufacturing. Different from mixed licorice extracts, no pigment fluctuation problem.
Powerful Soothing & Anti-Irritant Performance
Well-documented anti-inflammatory activity, effectively calm redness, stinging and itching of sensitive, irritated and sun-damaged skin. Can offset irritation from retinol, AHA/BHA and high-concentration vitamin-C formulas.
Excellent Water-Solubility
Fully soluble in water phase, easy to incorporate into aqueous systems such as toners, essences and aqueous gels, convenient for cosmetic R&D production.
Good Formulation Stability
Stable within cosmetic pH 4.5-7.5 range, fits most common skincare systems. Suitable for normal thermal production process, avoid long-time heating over 80℃.
Global Regulatory Compliance
Listed in China IECIC, EU CosIng, US CIR safety approved, meets cosmetic raw-material requirements for Asia, Europe and North America markets.
Complete Technical Document Support
Each batch is attached with COA, MSDS, TDS and HPLC spectrum, supporting cosmetic registration and third-party testing.
Flexible Supply Capacity
Support lab test sample, small trial order and mass bulk order, flexible packaging options for different customer demands.
How Dipotassium Glycyrrhizate Works On Skin
Dipotassium Glycyrrhizate inhibits cyclooxygenase and inflammatory mediators, suppresses histamine release, reduces local inflammatory reaction, without hormone-like side effects. It alleviates skin redness, burning and itching triggered by irritants, sun exposure and high-activity cosmetic ingredients. It protects keratinocytes from inflammatory damage and accelerates recovery of impaired skin barrier.
Topical application shows very low skin penetration, almost no systemic absorption risk under cosmetic usage concentration. It also helps reduce post-inflammatory red-mark and pigmentation risk, but it is not a primary brightening raw material.
Main Functions & Application Fields
Skin Benefits
- - Inhibit skin inflammatory response
- - Relieve skin redness, stinging and itching
- - Mitigate irritation from high-activity cosmetic ingredients
- - Calm UV-caused post-sun skin discomfort
- - Assist repair damaged sensitive skin barrier
- - Reduce post-inflammatory red marks
Suitable Finished Cosmetic Products
- - Sensitive-skin soothing serum & essence
- - Calming facial cream, lotion and gel
- - Soothing sheet mask & sleeping mask
- - After-sun repair skincare series
- - Irritation-reducing formula with AHA/BHA, retinol, vitamin-C
- - Gentle soothing toner & essence water
- - Itchy-relief scalp care products
- - Mild eye-care cosmetics
Formulation Guide: Dosage, Solubility & Compatibility Tips
Recommended dosage: Leave-on products (serum, cream, mask): 0.1%-1.0%, do not exceed 1.0% in finished cosmetics. Rinse-off products (cleanser, shampoo): 0.1%-0.5%.
Solubility & Adding Process: Water-phase soluble; dissolve in water phase at 45-60℃ is preferred; can dissolve at room temperature for simple aqueous formula. Avoid prolonged heating above 80℃. Add EDTA-2Na as chelating agent for high-electrolyte formulas to improve system stability.
Synergistic matching ingredients: Combine with panthenol, allantoin, hyaluronic acid to enhance soothing & barrier-repair effect; match with niacinamide, vitamin-C, exfoliating ingredients to reduce irritation risk.
Important Formulation Notes: - Avoid pH below 4.5, precipitation may occur. - Incompatible with high-concentration cationic surfactants, will generate insoluble complex and lose efficacy. - High salt content system may cause salting-out phenomenon. - It is water-soluble material, cannot directly add to oil phase.


Dipotassium Glycyrrhizate VS Common Soothing Raw Materials
| Item | Dipotassium Glycyrrhizate | Allantoin | Ammonium Glycyrrhizate | Glycyrrhetinic Acid |
|---|---|---|---|---|
| Typical Purity | ≥98% | ≥99% | ≥98% | ≥98% |
| Solubility | Water-soluble | Water-soluble | Water-soluble | Oil-soluble |
| Usual Dosage | 0.1-1.0% | 0.2-0.5% | 0.1-0.5% | 0.05-0.2% |
| Soothing Strength | Strong anti-inflammatory | Mild soothing | Medium-strong | Strong anti-inflammatory |
| Formula Limitation | Avoid cationic surfactants | Few restrictions | Sensitive to low pH | Only oil-phase addition |
| Cost Level | Medium | Low | Medium-low | High |
Packaging, MOQ & Global Shipping Details
- - Small package: 1kg / 5kg aluminium foil bag with inner PE bag
- - Bulk package: 25kg fiber drum with double inner plastic bags
- - MOQ: 1kg
- - Shipping: Global door-to-door service, support DHL, FedEx, air freight and sea freight
- - Custom packing: Custom label & packaging available for large bulk orders
- - Lead time: 3-7 working days for sample orders; 7-15 working days for bulk orders
Storage & Shelf-Life Standard
Storage Conditions
Keep container tightly sealed. Store in cool, dry and dark place. Prevent moisture absorption, high temperature and direct sunlight. This raw material is hygroscopic. Once opened, use as soon as possible.
Shelf Life
24 months under original sealed and proper storage conditions.
Certifications & Compliance Documents (COA, MSDS, TDS)
Our 98% Dipotassium Glycyrrhizate meets global cosmetic raw-material requirements:
- - Included in China IECIC existing cosmetic ingredient inventory
- - EU CosIng listed
- - US CIR safety assessment approved
- - Production managed under ISO22716 & GMP system
- - Each batch supplies COA, MSDS, TDS and HPLC chromatogram
- - Support third-party independent testing for customer verification
We supply cosmetic raw materials to cosmetic manufacturers across Europe, Southeast Asia, Middle East and other regions, providing stable bulk raw-material supply for skincare brands.
Frequently Asked Questions
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Q1: What is the stable pH range for dipotassium glycyrrhizate?
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Q2: Can dipotassium glycyrrhizate be used with vitamin-C, AHA/BHA or retinol?
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Q3: What is difference between dipotassium glycyrrhizate and licorice extract?
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Q4: Does dipotassium glycyrrhizate have whitening effect?
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Q5: What is your MOQ for wholesale order?
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Q6: Can you provide complete COA and MSDS documents?
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Q7: Why does dipotassium glycyrrhizate powder cake sometimes?
A: This material is hygroscopic. Keep sealed storage, control warehouse humidity. Sealed immediately after opening package to avoid moisture absorption.
Get Wholesale Quote & Free Testing Sample
We provide free lab test sample, complete technical documents and professional formulation suggestion for your cosmetic R&D team.
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Global Business Contact:
WhatsApp: 0086-18091843361
Official Website: www.aogebio.com
Factory Address: Xi'an, Shaanxi, China







