If you are sourcing high‑quality D‑Panthenol (Provitamin B5) cosmetic raw material for manufacturing, feel free to contact us. We provide lab‑test samples, full technical documents and practical formulation reference suggestions.
D-Panthenol (Vitamin B5) – Barrier Repair & Moisture Active
D‑Panthenol | Bulk Cosmetic‑Grade Provitamin B5 Raw Material Supplier
D‑Panthenol
Buy bulk D‑Panthenol, high‑quality cosmetic‑grade provitamin B5 raw material widely used for skincare and hair‑care product manufacturing. D‑Panthenol converts into pantothenic acid on skin surface, delivering deep moisturizing, soothing and barrier‑strengthening effects. It relieves skin discomfort caused by external irritation, sun exposure and dry environment, and improves hair softness while reducing split‑ends. Widely applied in moisturizing lotion, serum, after‑sun repair, sensitive‑skin care, shampoo, conditioner and gentle cleansing formulas. Manufactured under GMP‑compliant workshops, free R&D sample available, complete COA, MSDS, TDS documents supplied for cosmetic registration and formula R&D, worldwide bulk shipping service supported.
Product Specification
| Item | Specification |
|---|---|
| Product Name | D‑Panthenol |
| INCI Name | Panthenol |
| CAS No. | 81‑13‑0 |
| Molecular Formula | C₉H₁₉NO₄ |
| Molecular Weight | 205.25 |
| Appearance | Colorless to slightly yellow clear viscous liquid |
| Purity | ≥98.0% |
| Optical Rotation [α]₂₀ᴰ | +29.0° ~ +32.0° |
| Solubility | Fully miscible with water and alcohol; insoluble in oils |
| pH (10% Aqueous Solution) | 9.0‑11.0 |
| Water Content | ≤0.5% |
| Heavy Metals (as Pb) | ≤5 mg/kg |
| Residue on Ignition | ≤0.1% |
| Recommended Addition Range | Leave‑on skincare:1%‑5%; Hair care:0.5%‑3%; Rinse‑off products:0.2%‑2%; After‑sun & soothing formulas:2%‑5% |
| MOQ | 1kg |
| Shelf Life | 2 years under sealed proper storage |
What Is D‑Panthenol?
D‑Panthenol, commonly known as Provitamin B5, is a popular water‑soluble cosmetic active raw material. After penetrating into skin, D‑Panthenol transforms into pantothenic acid, an essential component of coenzyme A, supporting skin metabolism, moisturization and barrier health. It draws and retains moisture within stratum corneum, relieves dry, tight and irritated skin. For hair‑care applications, it penetrates hair cuticles, increases hair moisture content, improves softness and reduces brittle hair and split‑ends.
Our cosmetic‑grade D‑Panthenol features high D‑isomer content, low impurities and stable batch‑to‑batch consistency. It is highly suitable for sensitive‑skin formulas, after‑sun repair, post‑procedure gentle care, moisturizing skincare and various hair‑care products. Each batch provides full technical documents to support cosmetic filing and laboratory formula development.
Core Advantages Of Our D‑Panthenol
Deep Moisturizing & Skin‑Barrier Supporting
Penetrates stratum corneum to lock moisture, reduces transepidermal water loss, supports skin barrier integrity, alleviates dry‑caused tight and rough skin condition.
Excellent Soothing & Anti‑Irritation Performance
Relieves skin discomfort triggered by UV exposure, environmental stress and chemical irritation; widely used in after‑sun repair and sensitive‑skin soothing formulations.
Multi‑Benefit Hair‑Care Effect
Penetrates hair cuticle, replenishes hair moisture, enhances hair softness and luster, reduces brittleness and split‑ends, works well in shampoo, conditioner and hair treatment products.
Superior Water‑Phase Compatibility
Perfectly miscible with water‑phase ingredients, compatible with gels, toners, serums, emulsions and most aqueous cosmetic systems, easy to incorporate into diverse formulas.
Mild & Broad‑Formula Adaptability
Low‑irritation property, suitable for sensitive‑skin, baby‑care and clean‑beauty cosmetic lines; can be combined with humectants, repairing actives and plant extracts.
Reliable Quality & Full Technical Support
High purity ≥98.0%, strict batch‑by‑batch quality inspection, support third‑party independent lab testing. Provide COA, MSDS, TDS and practical cosmetic formulation suggestions for your R&D team.
How D‑Panthenol Works In Cosmetic Formulations
D‑Panthenol is water‑soluble raw material, add directly into water phase during production. When applied to skin, it converts to pantothenic acid, participates in skin metabolism, boosts hydration and soothes irritated skin. For hair, it penetrates hair shaft to retain moisture and improve hair texture.
It can produce obvious synergistic effects when compounded with glycerin, hyaluronic acid, allantoin and centella asiatica extract. Please conduct compatibility test and finished‑product stability assessment before mass production. Final performance is subject to dosage, formula pH and matching raw materials.
Main Application & Suitable End‑Products
Core Formulation Benefits
- -Provitamin B5 moisturizing for skin hydration and barrier maintenance
- -Soothe irritated skin, ideal for after‑sun and sensitive‑skin care
- -Nourish hair, improve softness and reduce split‑ends
- -Water‑soluble, easy to use in aqueous, gel and emulsion systems
- -Mild raw material for sensitive‑skin and gentle‑care cosmetic products
Recommended Finished Products
- -Moisturizing serum, facial lotion, cream and hydrating toner
- -After‑sun repair gel, mist and soothing skincare
- -Sensitive‑skin calming and barrier‑repair products
- -Gentle facial cleanser and rinse‑off skincare
- -Shampoo, hair conditioner and hair mask treatment
- -Baby gentle moisturizing and care products
- -Post‑treatment soothing skincare products
- -Gel mask, essence and water‑based cosmetic formulations
Formulation Guide: Dosage, Dispersion & Critical Notes
Recommended addition range: Leave‑on skincare:1%‑5%; Hair care:0.5%‑3%; Rinse‑off products:0.2%‑2%; After‑sun & soothing formulas:2%‑5%. Adjust dosage according to expected efficacy, skin‑feel requirement and local cosmetic regulatory requirements.
Processing method: D‑Panthenol is water‑phase raw material. Dissolve completely in water phase under normal stirring before emulsification. No high‑shear homogenization required. Avoid prolonged high‑temperature heating.
Suggested synergistic ingredients: Combine with glycerin, hyaluronic acid to enhance moisturizing effect; match with allantoin, centella asiatica extract to strengthen soothing performance; compound with ceramides for barrier‑repair formulas.
Important formulation reminders
- -Water‑soluble raw material, must be added into water phase, insoluble in oil phase.
- -Long‑term high‑temperature environment may cause raw material color deepening; processing temperature better controlled below 80℃.
- -Formula pH should keep within 5‑7 for optimal stability of D‑Panthenol.
- -Hygroscopic characteristic, seal tightly after opening and avoid moisture absorption.
- -Only for cosmetic raw‑material use. Finished‑product safety & stability test is mandatory before mass production.


Packaging, MOQ & Global Shipping
- -Small package: 1kg /5kg aluminum foil bag with inner PE bag
- -Bulk package: 25kg plastic drum
- -Custom package: Custom label service for large‑volume orders
- -MOQ: 1kg
- -Shipping: DHL, FedEx, air freight, sea freight, global door‑to‑door delivery
- -Lead time: 3‑7 working days for sample; 7‑15 working days for bulk order
Storage & Shelf‑Life
Storage Conditions
Store in tightly closed container. Keep in cool, dry place. Protect from high temperature, light and moisture. Seal well after opening.
Shelf Life
2 years under original sealed and proper storage environment.
Certifications & Documents
- -GMP compliant production workshop
- -COA, MSDS, TDS documents available for each batch
- -Accept third‑party lab testing
- -Qualified for moisturizing, soothing, hair‑care and sensitive‑skin raw‑material formulation
Frequently Asked Questions
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Q1: What is D‑Panthenol used for in cosmetics?
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Q2: Is D‑Panthenol water‑soluble?
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Q3: What is the typical dosage for soothing serum?
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Q4: What factors affect D‑Panthenol stability?
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Q5: Can you provide COA MSDS and free R&D samples?
A: Yes, please send inquiry via contact form or WhatsApp to get R&D samples and complete technical documents.
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Global Business Contact:
WhatsApp: 0086-18091843361
Official Website: www.aogebio.com
Factory Address: Xi'an, Shaanxi, China






