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D-Panthenol (Vitamin B5) – Barrier Repair & Moisture Active

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D-Panthenol is a vitamin B5 derivative that binds moisture, supports the skin barrier and calms irritation, making it a staple active in repair serums, creams and baby care.

  • Binds moisture and supports the skin barrier in repair formulas
  • Soothes irritation and suits sensitive-skin and baby products
  • Easy to use in serums, creams and shampoo systems

    D‑Panthenol | Bulk Cosmetic‑Grade Provitamin B5 Raw Material Supplier

    D‑Panthenol

    Buy bulk D‑Panthenol, high‑quality cosmetic‑grade provitamin B5 raw material widely used for skincare and hair‑care product manufacturing. D‑Panthenol converts into pantothenic acid on skin surface, delivering deep moisturizing, soothing and barrier‑strengthening effects. It relieves skin discomfort caused by external irritation, sun exposure and dry environment, and improves hair softness while reducing split‑ends. Widely applied in moisturizing lotion, serum, after‑sun repair, sensitive‑skin care, shampoo, conditioner and gentle cleansing formulas. Manufactured under GMP‑compliant workshops, free R&D sample available, complete COA, MSDS, TDS documents supplied for cosmetic registration and formula R&D, worldwide bulk shipping service supported.
    ✅ Provitamin B5 Skin‑Soothing & Moisturizing Agent ✅ Strengthen Skin Barrier & Reduce Skin Irritation ✅ Improve Hair Moisture, Softness & Anti‑Split‑End ✅ Excellent Water‑Phase Compatibility ✅ Promote Skin Comfort After Stress & Sun Exposure ✅ GMP Production Standard ✅ Global Door‑to‑Door Shipping
    D-Panthenol-Bulk-Cosmetic-Grade-Provitamin-B5-Raw-Material-Supplier

    Product Specification

    Item Specification
    Product Name D‑Panthenol
    INCI Name Panthenol
    CAS No. 81‑13‑0
    Molecular Formula C₉H₁₉NO₄
    Molecular Weight 205.25
    Appearance Colorless to slightly yellow clear viscous liquid
    Purity ≥98.0%
    Optical Rotation [α]₂₀ᴰ +29.0° ~ +32.0°
    Solubility Fully miscible with water and alcohol; insoluble in oils
    pH (10% Aqueous Solution) 9.0‑11.0
    Water Content ≤0.5%
    Heavy Metals (as Pb) ≤5 mg/kg
    Residue on Ignition ≤0.1%
    Recommended Addition Range Leave‑on skincare:1%‑5%; Hair care:0.5%‑3%; Rinse‑off products:0.2%‑2%; After‑sun & soothing formulas:2%‑5%
    MOQ 1kg
    Shelf Life 2 years under sealed proper storage

    What Is D‑Panthenol?

    D‑Panthenol, commonly known as Provitamin B5, is a popular water‑soluble cosmetic active raw material. After penetrating into skin, D‑Panthenol transforms into pantothenic acid, an essential component of coenzyme A, supporting skin metabolism, moisturization and barrier health. It draws and retains moisture within stratum corneum, relieves dry, tight and irritated skin. For hair‑care applications, it penetrates hair cuticles, increases hair moisture content, improves softness and reduces brittle hair and split‑ends.

    Our cosmetic‑grade D‑Panthenol features high D‑isomer content, low impurities and stable batch‑to‑batch consistency. It is highly suitable for sensitive‑skin formulas, after‑sun repair, post‑procedure gentle care, moisturizing skincare and various hair‑care products. Each batch provides full technical documents to support cosmetic filing and laboratory formula development.

    Core Advantages Of Our D‑Panthenol

    Deep Moisturizing & Skin‑Barrier Supporting

    Penetrates stratum corneum to lock moisture, reduces transepidermal water loss, supports skin barrier integrity, alleviates dry‑caused tight and rough skin condition.

    Excellent Soothing & Anti‑Irritation Performance

    Relieves skin discomfort triggered by UV exposure, environmental stress and chemical irritation; widely used in after‑sun repair and sensitive‑skin soothing formulations.

    Multi‑Benefit Hair‑Care Effect

    Penetrates hair cuticle, replenishes hair moisture, enhances hair softness and luster, reduces brittleness and split‑ends, works well in shampoo, conditioner and hair treatment products.

    Superior Water‑Phase Compatibility

    Perfectly miscible with water‑phase ingredients, compatible with gels, toners, serums, emulsions and most aqueous cosmetic systems, easy to incorporate into diverse formulas.

    Mild & Broad‑Formula Adaptability

    Low‑irritation property, suitable for sensitive‑skin, baby‑care and clean‑beauty cosmetic lines; can be combined with humectants, repairing actives and plant extracts.

    Reliable Quality & Full Technical Support

    High purity ≥98.0%, strict batch‑by‑batch quality inspection, support third‑party independent lab testing. Provide COA, MSDS, TDS and practical cosmetic formulation suggestions for your R&D team.

    How D‑Panthenol Works In Cosmetic Formulations

    D‑Panthenol is water‑soluble raw material, add directly into water phase during production. When applied to skin, it converts to pantothenic acid, participates in skin metabolism, boosts hydration and soothes irritated skin. For hair, it penetrates hair shaft to retain moisture and improve hair texture.

    It can produce obvious synergistic effects when compounded with glycerin, hyaluronic acid, allantoin and centella asiatica extract. Please conduct compatibility test and finished‑product stability assessment before mass production. Final performance is subject to dosage, formula pH and matching raw materials.

    Main Application & Suitable End‑Products

    Core Formulation Benefits

    • -Provitamin B5 moisturizing for skin hydration and barrier maintenance
    • -Soothe irritated skin, ideal for after‑sun and sensitive‑skin care
    • -Nourish hair, improve softness and reduce split‑ends
    • -Water‑soluble, easy to use in aqueous, gel and emulsion systems
    • -Mild raw material for sensitive‑skin and gentle‑care cosmetic products

    Recommended Finished Products

    • -Moisturizing serum, facial lotion, cream and hydrating toner
    • -After‑sun repair gel, mist and soothing skincare
    • -Sensitive‑skin calming and barrier‑repair products
    • -Gentle facial cleanser and rinse‑off skincare
    • -Shampoo, hair conditioner and hair mask treatment
    • -Baby gentle moisturizing and care products
    • -Post‑treatment soothing skincare products
    • -Gel mask, essence and water‑based cosmetic formulations

    Formulation Guide: Dosage, Dispersion & Critical Notes

    Recommended addition range: Leave‑on skincare:1%‑5%; Hair care:0.5%‑3%; Rinse‑off products:0.2%‑2%; After‑sun & soothing formulas:2%‑5%. Adjust dosage according to expected efficacy, skin‑feel requirement and local cosmetic regulatory requirements.

    Processing method: D‑Panthenol is water‑phase raw material. Dissolve completely in water phase under normal stirring before emulsification. No high‑shear homogenization required. Avoid prolonged high‑temperature heating.

    Suggested synergistic ingredients: Combine with glycerin, hyaluronic acid to enhance moisturizing effect; match with allantoin, centella asiatica extract to strengthen soothing performance; compound with ceramides for barrier‑repair formulas.

    Important formulation reminders

    • -Water‑soluble raw material, must be added into water phase, insoluble in oil phase.
    • -Long‑term high‑temperature environment may cause raw material color deepening; processing temperature better controlled below 80℃.
    • -Formula pH should keep within 5‑7 for optimal stability of D‑Panthenol.
    • -Hygroscopic characteristic, seal tightly after opening and avoid moisture absorption.
    • -Only for cosmetic raw‑material use. Finished‑product safety & stability test is mandatory before mass production.
    GMP ISO22716 Mango Butter Manufacturing WorkshopGMP ISO22716 Mango Butter Manufacturing WorkshopGMP ISO22716 Mango Butter Manufacturing Workshop

    Packaging, MOQ & Global Shipping

    Packaging, MOQ & Global Shipping Details (1)
    Packaging, MOQ & Global Shipping Details (1)
    Packaging, MOQ & Global Shipping Details (2)
    Packaging, MOQ & Global Shipping Details (2)
    • -Small package: 1kg /5kg aluminum foil bag with inner PE bag
    • -Bulk package: 25kg plastic drum
    • -Custom package: Custom label service for large‑volume orders
    • -MOQ: 1kg
    • -Shipping: DHL, FedEx, air freight, sea freight, global door‑to‑door delivery
    • -Lead time: 3‑7 working days for sample; 7‑15 working days for bulk order

    Storage & Shelf‑Life

    Storage Conditions

    Store in tightly closed container. Keep in cool, dry place. Protect from high temperature, light and moisture. Seal well after opening.

    Shelf Life

    2 years under original sealed and proper storage environment.

    Certifications & Documents

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    • -GMP compliant production workshop
    • -COA, MSDS, TDS documents available for each batch
    • -Accept third‑party lab testing
    • -Qualified for moisturizing, soothing, hair‑care and sensitive‑skin raw‑material formulation

    Frequently Asked Questions

    • Q1: What is D‑Panthenol used for in cosmetics?

    • Q2: Is D‑Panthenol water‑soluble?

    • Q3: What is the typical dosage for soothing serum?

    • Q4: What factors affect D‑Panthenol stability?

    • Q5: Can you provide COA MSDS and free R&D samples?

      A: Yes, please send inquiry via contact form or WhatsApp to get R&D samples and complete technical documents.

    Get Wholesale Price & R&D Sample

    If you are sourcing high‑quality D‑Panthenol (Provitamin B5) cosmetic raw material for manufacturing, feel free to contact us. We provide lab‑test samples, full technical documents and practical formulation reference suggestions.

    Send Inquiry For Sample & Bulk Price

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    Global Business Contact:

    WhatsApp: 0086-18091843361

    Official Website: www.aogebio.com

    Factory Address: Xi'an, Shaanxi, China