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Copper Peptide (GHK-Cu)
Copper Tripeptide-1 for Skin Repair, Anti-Aging & Scalp Care | Bulk Cosmetic Peptide Wholesale
95% Copper Peptide (GHK-Cu) Powder CAS 49557-75-7 | Bulk Cosmetic Raw Material Supplier
Copper Peptide (GHK-Cu)
Buy bulk Copper Peptide GHK-Cu (Copper Tripeptide-1) powder CAS 49557-75-7. ≥95% chelated complex, water-soluble cosmetic peptide raw material for skin repairing, anti-aging formulation and scalp care. Compliant with IECIC & EU CosIng. ISO22000 & GMP-managed production, free sample available, global bulk supply.Product Specification
| Item | Specification |
|---|---|
Product Name |
Copper Peptide (GHK-Cu) |
INCI Name |
Copper Tripeptide-1 |
CAS No. |
49557-75-7 |
Molecular Formula |
C₁₄H₂₂CuN₆O₄ |
Molecular Weight |
401.91 g/mol |
Purity |
≥95.0% (HPLC, Chelated GHK-Cu complex) |
Appearance |
Blue-green fine crystalline powder |
Solubility |
Highly soluble in water |
Recommended Addition Range |
Leave-on formulations: 0.05%-0.5%; Intensive-type formulations: 0.5%-1.0% |
MOQ |
1g |
Shelf Life |
2 years under proper sealed storage (2-8℃ recommended for long-term preservation) |
What Is Copper Peptide (GHK-Cu)?
Copper Peptide GHK-Cu, also known as Copper Tripeptide-1 (CAS 49557-75-7), is a bio-active chelated complex formed by tripeptide Gly-His-Lys bound with copper ion. This peptide-mineral complex can be found naturally within human plasma.
As a widely-adopted cosmetic peptide raw material, GHK-Cu is commonly used in anti-aging and repairing cosmetic formulations. Relevant literature indicates it may support fibroblast activity and help regulate skin inflammatory response. Compared with some irritating anti-aging ingredients, GHK-Cu is considered mild for formulation development, and can be applied in sensitive-skin compatible formulas and post-beauty-instrument skincare products.
We are a China-based bulk supplier providing ≥95% GHK-Cu powder for cosmetic manufacturers worldwide. This raw material is widely used in serum, cream, mask, post-procedure care formula and hair-care products. We supply lab test samples, full COA, MSDS, TDS documents and worldwide door-to-door delivery service.
Core Advantages Of Our ≥95% Copper Peptide (GHK-Cu)
cosmetic-Grade ≥95% HPLC Chelated GHK-Cu Complex
HPLC testing focuses on actual chelated complex content, with strict control over un-chelated free-copper ion and free peptide residues. Stable batch performance for high-end cosmetic manufacturing, reducing risks of color shift brought by excessive free-copper impurities.
Multi-Purpose Peptide For Formulation Development
Supported by published studies, GHK-Cu can be incorporated into formulas intended to support dermal matrix condition, soothe irritated skin state, and assist skin recovery after external stress. It is also popularly added into scalp-care formulas for scalp micro-environment conditioning.
Mild Formulation Ingredient
No known photosensitivity under normal cosmetic usage dosage. It can be used in both day-time and night-time cosmetic formulas, and can be compounded with retinol-containing systems with proper production process design.
Good Water-Soluble Property
Fully dissolvable in water phase, easy to incorporate into essence, toner, gel and other aqueous cosmetic systems.
Global Cosmetic Regulation Compliance
Listed in China IECIC inventory and EU CosIng database, meets raw-material requirements for Asian, European and North-American cosmetic markets.
Complete Technical Document Support
Each batch is accompanied by COA, MSDS, TDS and HPLC test report, supporting cosmetic registration and third-party lab verification.
Flexible Supply Options
Available for lab sample testing, small trial orders and mass bulk orders, with multiple packaging selections for different customer demands.
How Copper Peptide (GHK-Cu) Works In Cosmetic Formulations
GHK-Cu functions as cell-signaling peptide ingredient in cosmetic formulas. Research data shows it may activate fibroblast and modulate the expression of dermal-related proteins, helping maintain skin matrix condition.
It can regulate inflammatory factors, which makes it suitable for formulas aiming to ease skin discomfort caused by external stimulus or beauty-instrument operations. It also exhibits antioxidant properties to help counter free-radical pressure. When used in scalp-care products, it helps condition scalp micro-environment.
Under recommended cosmetic addition amount, trans-dermal systemic absorption is expected to be minimal. Individuals with copper metabolism disorders should avoid end-products containing this ingredient.
Main Formulation Benefits & Application Fields
Formulation Benefits
- - Support collagen & elastin-related synthesis for anti-aging oriented formulas
- - Help maintain skin firmness condition
- - Suitable for formulas for skin recovery after beauty-instrument operations
- - Assist to soothe irritated skin status
- - Offer antioxidant support against free-radical impact
- - Condition scalp micro-environment for hair-care formulas
Suitable End-Product Formulations
- - Anti-aging serum & essence
- - Firming facial cream, lotion and gel
- - Post-beauty-instrument repairing skincare
- - Soothing repairing mask
- - Anti-aging toner & essence water
- - Mild skincare series for sensitive-skin oriented formulas
- - Scalp conditioning & hair-care products
- - High-end eye-care cosmetic formulas
Formulation Guide: Dosage, Solubility & Compatibility Tips
Recommended addition range: General leave-on products (serum, cream, mask): 0.05%-0.5%. Intensive-type formulations: 0.5%-1.0%. Do not exceed 1.0% in finished cosmetic products.
Solubility & Adding Process: Water-phase soluble. Add at ≤40℃ in the final production step. Avoid prolonged high-temperature heating, high heat may trigger peptide decomposition and color darkening.
Suggested synergistic ingredients: Combine with panthenol, allantoin, dipotassium glycyrrhizate to boost formula soothing and barrier-support performance; match with hyaluronic acid for moisturizing effect. Can cooperate with retinol within separate feeding processes for compound anti-aging formulas.
Important Formulation Notes: - Optimal stable pH scope: 6.0-7.5. Strong acid or strong alkali environment may result in peptide decomposition and color change. - Avoid direct mixing with high-concentration L-Ascorbic Acid (pure Vitamin-C), redox reaction may occur and deactivate both active substances. Vitamin-C derivatives are acceptable for compounding. - Keep away from EDTA-2Na and other strong chelating agents; chelators will capture copper ion and weaken GHK-Cu performance. - Strong-oxidizing preservative systems are not recommended; select mild preservative solutions. - Light-sensitive raw material; opaque packaging is suggested for finished goods.
GHK-Cu VS Common Anti-Aging Peptides & Cosmetic Actives
| Item | GHK-Cu (Copper Tripeptide-1) | Matrixyl 3000 | Argireline | Retinol |
|---|---|---|---|---|
| Typical Purity | ≥95% (Chelated complex) | ≥98% | ≥98% | 99% |
| Solubility | Water-soluble | Water-soluble | Water-soluble | Oil-soluble |
| Usual Addition Range | 0.05-1.0% | 2-5% | 3-8% | 0.1-0.5% |
| Core Formulation Value | Matrix support + skin conditioning | Collagen-signaling peptide | Muscle-relax oriented anti-wrinkle | Keratinocyte turnover regulation |
| Irritation Potential | Very low | Low | Very low | Medium-High |
| Photosensitivity | None | None | None | Yes |
| Formulation Limitation | No EDTA, avoid pure L-Ascorbic acid, light-sensitive | Few restrictions | Few restrictions | Light-sensitive, avoid low-pH |
| Cost Level | High | Medium | Medium | Low-Medium |
Packaging, MOQ & Global Shipping Details
- - Small package: 1g / 5g /10g aluminium foil bag with inner PE bag
- - Bulk package: 100g / 500g /1kg aluminium foil bag; 5kg fiber drum with double inner plastic bags
- - MOQ: 1g
- - Shipping: Global door-to-door service, support DHL, FedEx, air freight and sea freight
- - Custom packing: Custom label & packaging available for large bulk orders
- - Lead time: 3-7 working days for sample orders; 7-15 working days for bulk orders
Storage & Shelf-Life Standard
Storage Conditions
Keep container tightly sealed. Store in cool, dry and dark environment. Long-term storage recommend 2-8℃ refrigeration. Protect from light, high temperature and moisture. This peptide raw material is light-sensitive and easy to degrade under heat exposure. Once opened, use up as soon as possible.
Shelf Life
24 months under original sealed and proper storage conditions.
Certifications & Compliance Documents (COA, MSDS, TDS)
Our ≥95% Copper Peptide (GHK-Cu) complies with global cosmetic raw-material standards:
- - Listed in China IECIC existing cosmetic ingredient inventory
- - EU CosIng database listed
- - Production under ISO22000 & GMP management system
- - Each batch provides COA, MSDS, TDS and HPLC chromatogram
- - Support third-party independent lab testing for customer verification
We supply cosmetic peptide raw materials to cosmetic manufacturers across Europe, Southeast Asia, Middle East and other regions, providing stable bulk raw-material supply for high-end skincare brands.
Frequently Asked Questions
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Q1: What is the stable pH range for GHK-Cu?
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Q2: Can GHK-Cu be mixed with vitamin C?
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Q3: Why does GHK-Cu powder turn dark-green or fade?
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Q4: Is GHK-Cu suitable for sensitive-skin formulas?
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Q5: What is your MOQ for wholesale order?
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Q6: Can you provide complete COA and MSDS documents?
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Q7: Can GHK-Cu be used with retinol?
A: Yes, they can bring synergistic formulation benefits. It is suggested to add them separately under low-temperature process; retinol is usually for night formulas while GHK-Cu fits both day & night systems.
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