Leave Your Message

Oligopeptide-34 For Thicker, Fuller Hair

Products Name Oligopeptide-34
CAS No 1228379-73-4
INCI Name Oligopeptide-34
Specification ≥98% (HPLC)
Molecular Weight ~1100-1300 g/mol (sequence-dependent)
Chemical Formula Proprietary peptide sequence
Appearance White to off-white powder
Solubility Soluble in water and aqueous solutions
    aogebio Diethylamino Hydroxybenzoyl Hexyl Benzoate
    01

    Product Description

    I. Mechanism of Action (MOA)
    Oligopeptide-34 is a biomimetic peptide specifically engineered to target multiple pathways of hair growth and follicle health:

    Wnt/β-catenin Pathway Activation: Promotes hair follicle development and cycling by activating key signaling pathways

    Growth Factor Stimulation: Increases expression of VEGF and FGF-7, enhancing blood supply and follicular cell proliferation
    Anti-apoptotic Effects: Protects hair follicle cells from programmed cell death by regulating Bcl-2/Bax ratio

    Hair Cycle Regulation: Extends anagen (growth) phase and delays transition to catagen (regression) phase

    II. In Vitro Efficacy Data
    Follicle Organ Culture:
    Increased hair shaft elongation by 189% in human hair follicle organ culture
    Extended anagen phase duration by 67% compared to control

    Cell Proliferation Studies:
    Stimulated dermal papilla cell proliferation by 156% at 10 μg/mL
    Enhanced VEGF secretion by 203% in follicle models

    Gene Expression Analysis:
    Upregulated β-catenin signaling by 178%
    Increased FGF-7 expression by 142%

    III. Clinical Results
    6-Month Hair Growth Study (n=85, 5% Oligopeptide-34 solution):
    +38.7 hairs/cm² hair density increase
    +31.2% improvement in hair diameter
    89% of subjects showed visible hair density improvement
    78% reduction in daily hair shedding

    12-Week Androgenetic Alopecia Trial:
    Significant improvement in Sinclair hair stage scores
    43% increase in anagen/telogen ratio
    92% patient satisfaction rate for hair thickness

    Safety & Compatibility

    Thickeners

    Safety Profile

    *Non-irritating (HRIPT confirmed) *Non-comedogenic *Dermatologist tested *Suitable for sensitive scalp
    Actives

    Formulation Compatibility

    *pH stable (5.0-7.0)
    *Compatible with minoxidil, caffeine, saw palmetto
    *Thermal stable up to 45°C
    *Synergistic with other hair growth peptides
    aogebio Diethylamino Hydroxybenzoyl Hexyl Benzoate
    01

    Recommended Dosage & Formulations

    Effective Concentration: 3-7% in final product

    Optimal Formulations:
    Hair growth serums and lotions
    Scalp treatments
    Anti-hair loss shampoos and conditioners
    Hair density boosters

    Application: Once daily to affected scalp areas

    Summary & Key Selling Points

    Applications1
    01

    Multi-target Hair Growth

    Activates multiple pathways for comprehensive follicular stimulation
    Applications3
    01

    Clinically Proven Efficacy

    Demonstrated significant improvements in hair density and thickness
    Applications5
    03

    Superior Safety Profile

    Well-tolerated even on sensitive scalp
    Applications5
    03

    Science-backed Innovation

    Supported by robust in vitro and clinical data
    storage

    Storage

    Store in a closed container at a dry place at room temperature.

    gmo1

    Animal Testing

    Not animal tested

    vegetarian1

    Vegan

    Does not contain animal-derived components

    gmo

    GMO

    No data available

    Leave Your Message