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Octapeptide-11 Facial Treatment Professional Skin Renewal

Products Name Octapeptide-11
INCI Name Octapeptide-11
Specification ≥95% (HPLC)
Molecular Weight ~850-900 g/mol
Chemical Formula Custom peptide sequence (C₃₈H₆₂N₁₂O₁₂ range)
Appearance White to off-white lyophilized powder
Solubility  Soluble in water
    giga-powder-(10)
    01

    Product Description

    1. Mechanism of Action (MOA)
    Octapeptide-11 is a novel synthetic peptide specifically engineered to target skin pigmentation and melanogenesis through advanced biomimetic technology:

    Melanogenesis Regulation
    Inhibits α-MSH (melanocyte-stimulating hormone) binding to MC1R receptors
    Reduces tyrosinase activity and expression
    Suppresses MITF (microphthalmia-associated transcription factor) signaling pathway
    Anti-Inflammatory Action
    Decreases pro-inflammatory cytokine production
    Reduces UV-induced skin inflammation
    Inhibits prostaglandin synthesis

    Antioxidant Protection
    Scavenges free radicals and reactive oxygen species
    Protects melanocytes from oxidative stress
    Prevents UV-induced DNA damage

    2. In Vitro Efficacy Data
    Melanogenesis Inhibition
    76% reduction in tyrosinase activity
    68% decrease in melanin synthesis
    82% inhibition of α-MSH induced pigmentation

    Anti-Inflammatory Studies
    71% reduction in IL-1α production
    65% decrease in PGE2 synthesis
    58% suppression of TNF-α expression

    Cellular Protection
    2.3-fold increase in antioxidant capacity
    47% reduction in UV-induced DNA damage
    Enhanced cell viability under oxidative stress

    3. Clinical Results
    28-56 day clinical studies demonstrate:

    Pigmentation Improvement
    42% reduction in melanin index
    51% improvement in skin brightness
    38% decrease in spot area and intensity

    Skin Quality Parameters
    67% improvement in skin tone evenness
    45% enhancement in skin smoothness
    89% of subjects reported more radiant complexion

    Overall Results
    93% satisfaction with brightening effects
    87% reported reduced appearance of age spots
    Significant improvement in overall skin clarity

    Safety & Compatibility

    Thickeners

    Safety Profile

    *Non-irritating (HRIPT confirmed) *Non-sensitizing at recommended concentrations *Suitable for all skin types including sensitive skin
    Actives

    Formulation Compatibility

    *PH stability range: 4.5-7.0
    *Compatible with common cosmetic ingredients: Vitamin C and derivatives
    Niacinamide
    Other brightening agents
    Hyaluronic acid
    Antioxidants
    giga-powder-(10)
    01

    Recommended Usage & Formulations

    Optimal Concentration: 2-4%

    Preferred Formulations
    Brightening serums and essences
    Spot correction treatments
    Age spot correctors
    Even skin tone creams
    O/W emulsions and gels

    Application Frequency
    Twice daily for optimal results
    Morning use recommended with sunscreen

    Summary & Key Selling Points

    Applications1
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    Advanced Brightening Technology

    *Multi-target approach to melanogenesis regulation *Comprehensive pigmentation control
    Applications3
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    Clinically Proven Efficacy

    *Significant reduction in melanin index *Improved skin brightness and tone evenness *Effective spot correction
    Applications5
    03

    Superior Safety Profile

    *Gentle yet effective brightening action *Suitable for long-term use
    Applications5
    03

    Market Differentiation

    *Innovative peptide-based brightening technology *Strong scientific evidence base *Premium skincare positioning
    storage

    Storage

    Store in a closed container at a dry place at room temperature.

    gmo1

    Animal Testing

    Not animal tested

    vegetarian1

    Vegan

    Does not contain animal-derived components

    gmo

    GMO

    No data available

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