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Acetyl Hexapeptide-38 Targeted Anti-Aging Treatment

Products Name Acetyl Hexapeptide-38
INCI Name Acetyl Hexapeptide-38
Specification ≥98% (HPLC)
Molecular Weight ~700-750 g/mol
Chemical Formula  Custom peptide sequence (C₃₀H₅₀N₁₀O₉ range)
Appearance  White to off-white lyophilized powder
Solubility Soluble in water
    AOGEBIO Nano Titanium Dioxide
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    Product Description

    1. Mechanism of Action (MOA)
    Acetyl Hexapeptide-38 is a novel synthetic peptide specifically engineered to target multiple pathways of skin aging through advanced biomimetic technology:

    Extracellular Matrix Synthesis
    Stimulates collagen I, III and IV production
    Enhances fibronectin and elastin synthesis
    Activates TGF-β signaling pathways
    Cellular Communication
    Modulates integrin-mediated cell signaling
    Promotes fibroblast-keratinocyte cross-talk
    Supports natural cellular repair mechanisms

    Protective Functions
    Reduces matrix metalloproteinase activity
    Enhances antioxidant defense systems
    Strengthens skin barrier integrity

    2. In Vitro Efficacy Data
    Collagen Production Studies
    148% increase in collagen I synthesis
    132% enhancement in collagen III production
    87% upregulation in fibronectin expression

    Cellular Function Analysis
    2.2-fold improvement in fibroblast viability
    71% enhancement in cell migration capacity
    Significant reduction in senescence markers

    Protective Effects
    65% reduction in MMP-1 activity
    78% decrease in reactive oxygen species
    Enhanced protection against UV-induced damage

    3. Clinical Results
    28-56 day clinical studies demonstrate:

    Wrinkle Reduction
    36% reduction in wrinkle depth
    41% improvement in skin smoothness
    34% enhancement in skin elasticity

    Skin Quality Parameters
    63% increase in skin hydration
    47% improvement in skin firmness
    85% of subjects reported improved skin radiance

    Overall Improvement
    92% satisfaction with anti-aging results
    88% reported visibly younger-looking skin
    Significant improvement in skin texture and tone

    Safety & Compatibility

    Thickeners

    Safety Profile

    *Non-irritating (HRIPT confirmed) *Non-sensitizing at recommended concentrations *Suitable for sensitive skin types
    Actives

    Formulation Compatibility

    *PH stability range: 4.0-7.2
    *Compatible with common cosmetic ingredients: Hyaluronic acid and derivatives
    Vitamin C and derivatives
    Niacinamide
    Other peptide complexes
    Botanical extracts
    AOGEBIO Nano Titanium Dioxide
    01

    Recommended Usage & Formulations

    Optimal Concentration: 3-5%

    Preferred Formulations
    Anti-aging serums and concentrates
    Firming creams and lotions
    Eye contour treatments
    O/W emulsions
    Treatment ampoules

    Application Frequency
    Twice daily for optimal results
    Suitable for long-term continuous use

    Summary & Key Selling Points

    Applications1
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    Multi-Target Technology

    *Addresses collagen synthesis and cellular communication *Provides comprehensive anti-aging benefits
    Applications3
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    Clinically Proven Efficacy

    *Significant reduction in wrinkle depth *Improved skin elasticity and firmness *Enhanced skin hydration and radiance
    Applications5
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    Superior Safety Profile

    *Excellent skin tolerance *Broad formulation compatibility
    Applications5
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    Market Differentiation

    *Advanced peptide technology with proven results *Multi-functional anti-aging approach *Ideal for premium skincare positioning
    storage

    Storage

    Store in a closed container at a dry place at room temperature.

    gmo1

    Animal Testing

    Not animal tested

    vegetarian1

    Vegan

    Does not contain animal-derived components

    gmo

    GMO

    No data available

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